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immunohistochemical analysis  (Human Protein Atlas)

 
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    Human Protein Atlas immunohistochemical analysis
    Immunohistochemical Analysis, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/immunohistochemical+ihc+analysis/analysis+immunohistochemical/pm42270911-155-0-4
    Average 86 stars, based on 1 article reviews
    immunohistochemical analysis - by Bioz Stars, 2026-10
    86/100 stars

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    Related Articles

    Immunohistochemical staining:

    Article Title: Integrative bioinformatics and experimental validation unveil CRISP3 as a hypoxia-, epithelial mesenchymal transition-, and immune-related prognostic biomarker and therapeutic target in breast cancer
    Article Snippet: .. To confirm these findings at the protein level, we performed immunohistochemical (IHC) analysis using data from the Human Protein Atlas (HPA). ..

    Article Title: Prognostic value of a circadian rhythm-related gene signature in breast cancer patients: A retrospective cohort study
    Article Snippet: .. Immunohistochemical (IHC) analysis was implemented on the expression of key genes identified through Cox models utilizing the Human Protein Atlas database ( www.proteinatlas.org/ ). ..

    Article Title: Discovery of guaianolide-eudesmanolide dimers as antihepatoma agents by targeting NEURL1B to disrupt the DLL1/Notch signaling pathway.
    Article Snippet: .. Immunohistochemical (IHC) analysis from Human Protein Atlas (HPA) database manifested that NEURL1B expression was significantly higher in HCC tissues than in normal tissues. (Fig. S2e). ..

    Article Title: Functional analysis and verification of GYG2 in oncolytic virus-infected glioma.
    Article Snippet: .. Down-regulating GYG2 has antitumor effect in vitro Using immunohistochemical (IHC) analysis of clinical glioma samples from the Human Protein Atlas (HPA) data, we observed that GYG2 expression was significantly higher in glioma tissues compared to normal cerebral cortex tissues (Figure 7A). ..

    Article Title: Stage-dependent EZH2 methylation correlates with immune polarization, metabolic suppression, and unfavorable outcomes in hepatocellular carcinoma
    Article Snippet: .. Immunohistochemical (IHC) analysis from the Human Protein Atlas further confirmed the increased EZH2 protein expression in tumor samples. ..

    Article Title: Prognostic value of a circadian rhythm-related gene signature in breast cancer patients: A retrospective cohort study
    Article Snippet: .. Immunohistochemical (IHC) analysis was implemented on the expression of key genes identified through Cox models utilizing the Human Protein Atlas database (www.proteinatlas.org/). ..

    Article Title: IGF2BP2 stabilized by USP7 promotes cancer-associated fibroblast activation and attenuates gemcitabine sensitivity in PDAC
    Article Snippet: .. The immunohistochemical (IHC) analysis of IGF2BP2 in the Human Protein Atlas (HPA) database demonstrated similar results (Figure S1B). ..

    Immunohistochemistry:

    Article Title: Integrative bioinformatics and experimental validation unveil CRISP3 as a hypoxia-, epithelial mesenchymal transition-, and immune-related prognostic biomarker and therapeutic target in breast cancer
    Article Snippet: .. To confirm these findings at the protein level, we performed immunohistochemical (IHC) analysis using data from the Human Protein Atlas (HPA). ..

    Article Title: Prognostic value of a circadian rhythm-related gene signature in breast cancer patients: A retrospective cohort study
    Article Snippet: .. Immunohistochemical (IHC) analysis was implemented on the expression of key genes identified through Cox models utilizing the Human Protein Atlas database ( www.proteinatlas.org/ ). ..

    Article Title: Discovery of guaianolide-eudesmanolide dimers as antihepatoma agents by targeting NEURL1B to disrupt the DLL1/Notch signaling pathway.
    Article Snippet: .. Immunohistochemical (IHC) analysis from Human Protein Atlas (HPA) database manifested that NEURL1B expression was significantly higher in HCC tissues than in normal tissues. (Fig. S2e). ..

    Article Title: Functional analysis and verification of GYG2 in oncolytic virus-infected glioma.
    Article Snippet: .. Down-regulating GYG2 has antitumor effect in vitro Using immunohistochemical (IHC) analysis of clinical glioma samples from the Human Protein Atlas (HPA) data, we observed that GYG2 expression was significantly higher in glioma tissues compared to normal cerebral cortex tissues (Figure 7A). ..

    Article Title: Stage-dependent EZH2 methylation correlates with immune polarization, metabolic suppression, and unfavorable outcomes in hepatocellular carcinoma
    Article Snippet: .. Immunohistochemical (IHC) analysis from the Human Protein Atlas further confirmed the increased EZH2 protein expression in tumor samples. ..

    Article Title: Prognostic value of a circadian rhythm-related gene signature in breast cancer patients: A retrospective cohort study
    Article Snippet: .. Immunohistochemical (IHC) analysis was implemented on the expression of key genes identified through Cox models utilizing the Human Protein Atlas database (www.proteinatlas.org/). ..

    Article Title: IGF2BP2 stabilized by USP7 promotes cancer-associated fibroblast activation and attenuates gemcitabine sensitivity in PDAC
    Article Snippet: .. The immunohistochemical (IHC) analysis of IGF2BP2 in the Human Protein Atlas (HPA) database demonstrated similar results (Figure S1B). ..

    Expressing:

    Article Title: Prognostic value of a circadian rhythm-related gene signature in breast cancer patients: A retrospective cohort study
    Article Snippet: .. Immunohistochemical (IHC) analysis was implemented on the expression of key genes identified through Cox models utilizing the Human Protein Atlas database ( www.proteinatlas.org/ ). ..

    Article Title: Discovery of guaianolide-eudesmanolide dimers as antihepatoma agents by targeting NEURL1B to disrupt the DLL1/Notch signaling pathway.
    Article Snippet: .. Immunohistochemical (IHC) analysis from Human Protein Atlas (HPA) database manifested that NEURL1B expression was significantly higher in HCC tissues than in normal tissues. (Fig. S2e). ..

    Article Title: Functional analysis and verification of GYG2 in oncolytic virus-infected glioma.
    Article Snippet: .. Down-regulating GYG2 has antitumor effect in vitro Using immunohistochemical (IHC) analysis of clinical glioma samples from the Human Protein Atlas (HPA) data, we observed that GYG2 expression was significantly higher in glioma tissues compared to normal cerebral cortex tissues (Figure 7A). ..

    Article Title: Stage-dependent EZH2 methylation correlates with immune polarization, metabolic suppression, and unfavorable outcomes in hepatocellular carcinoma
    Article Snippet: .. Immunohistochemical (IHC) analysis from the Human Protein Atlas further confirmed the increased EZH2 protein expression in tumor samples. ..

    Article Title: Prognostic value of a circadian rhythm-related gene signature in breast cancer patients: A retrospective cohort study
    Article Snippet: .. Immunohistochemical (IHC) analysis was implemented on the expression of key genes identified through Cox models utilizing the Human Protein Atlas database (www.proteinatlas.org/). ..

    In Vitro:

    Article Title: Functional analysis and verification of GYG2 in oncolytic virus-infected glioma.
    Article Snippet: .. Down-regulating GYG2 has antitumor effect in vitro Using immunohistochemical (IHC) analysis of clinical glioma samples from the Human Protein Atlas (HPA) data, we observed that GYG2 expression was significantly higher in glioma tissues compared to normal cerebral cortex tissues (Figure 7A). ..



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    LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry <t>(IHC)</t> of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown
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    Image Search Results


    LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry (IHC) of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown

    Journal: Discover Oncology

    Article Title: Spatial transcriptomics of urothelial carcinoma with basal/squamous differentiation identifies Galectin-7 as a specific marker of squamous lineage commitment

    doi: 10.1007/s12672-026-04927-z

    Figure Lengend Snippet: LGALS7 is selectively expressed in Ba/Sq differentiation and promotes squamous carcinoma cell proliferation. A The H&E image from Fig. B is shown again, with a red box indicating the region analyzed in this figure. Spatial transcriptomic maps display TP63 and LGALS7 expression patterns within the boxed region, corresponding to the UC–Ba/Sq interface. B Cluster-level expression of TP63 and LGALS7. C Immunohistochemistry (IHC) of the cystectomy specimen showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 1 mm. D Western blot showing Galectin-7 expression across cancer cell lines (left), and immunofluorescence (IF) of SCaBER cells showing cytoplasmic localization (right). E Proliferation assay of SCaBER cells following LGALS7 knockdown

    Article Snippet: To assess the diagnostic performance of Galectin-7 in identifying squamous differentiation within urothelial carcinoma (UC), we performed immunohistochemical (IHC) analysis on 28 cases of Ba/Sq UC and 64 cases of pure UC.

    Techniques: Expressing, Immunohistochemistry, Western Blot, Immunofluorescence, Proliferation Assay, Knockdown

    Diagnostic and prognostic value of Galectin-7 in urothelial carcinoma. A Immunohistochemistry (IHC) for p63 and Galectin-7 in UC with Ba/Sq features ( n = 28) and UC without Ba/Sq ( n = 64). B Immunohistochemistry (IHC) of three representative UC with Ba/Sq differentiation cases showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 100 μm. C Summary of key clinicopathological parameters associated with Galectin-7 (G7) expression. Detailed clinicopathological data are provided in Supplementary Table 1. Kaplan–Meier analysis of progression-free survival stratified by Galectin-7 expression

    Journal: Discover Oncology

    Article Title: Spatial transcriptomics of urothelial carcinoma with basal/squamous differentiation identifies Galectin-7 as a specific marker of squamous lineage commitment

    doi: 10.1007/s12672-026-04927-z

    Figure Lengend Snippet: Diagnostic and prognostic value of Galectin-7 in urothelial carcinoma. A Immunohistochemistry (IHC) for p63 and Galectin-7 in UC with Ba/Sq features ( n = 28) and UC without Ba/Sq ( n = 64). B Immunohistochemistry (IHC) of three representative UC with Ba/Sq differentiation cases showing diffuse p63 positivity in both urothelial carcinoma (UC) and Ba/Sq-differentiated tumor components, and selective Galectin-7 expression restricted to Ba/Sq-differentiated tumor nests. Scale bars, 100 μm. C Summary of key clinicopathological parameters associated with Galectin-7 (G7) expression. Detailed clinicopathological data are provided in Supplementary Table 1. Kaplan–Meier analysis of progression-free survival stratified by Galectin-7 expression

    Article Snippet: To assess the diagnostic performance of Galectin-7 in identifying squamous differentiation within urothelial carcinoma (UC), we performed immunohistochemical (IHC) analysis on 28 cases of Ba/Sq UC and 64 cases of pure UC.

    Techniques: Diagnostic Assay, Immunohistochemistry, Expressing